Antimicrobial peptides
BioChemEntityEndogenous peptides that defend against microbes yet can drive inflammation, acting as antimicrobial, immunomodulatory, and microbiome‑shaping signals.
Biochemical Entity
15 entities in this category
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Beta-defensins
BioChemEntityA family of cationic antimicrobial proteins with distinct roles in baseline defence, inducible microbiome‑responsive immunity, and broad‑spectrum pathogen control.
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Blood plasma
BioChemEntityLiquid component of blood containing platelets and proteins, separated and concentrated during PRP and iPRF treatments.
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Cutibacterium acnes
BioChemEntityThe dominant commensal on sebaceous skin — active manufacturer of barrier lipids via PPARα signalling, principal acidifier of the sebaceous skin surface, and endogenous antioxidant provider.
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Glycosaminoglycan
BioChemEntityGlycosaminoglycans (GAGs) are the dermis's primary humectants, binding water, while also organising collagen architecture and regulating growth-factor and cytokine signalling.
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Heparan sulfate proteoglycans
BioChemEntityGlycosaminoglycan-bearing proteins distributed across the dermal ECM and basement membrane that store and regulate growth factors including FGF2, FGF7, FGF10, and VEGF in a protected on-site depot.
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Malonyl coenzyme A
BioChemEntityA glucose‑derived metabolite that inhibits CPT‑1, suppressing fatty‑acid oxidation and diverting lipids toward storage when carbohydrate supply is high.
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Platelet-derived growth factor
BioChemEntityA family of growth factors stored in platelet alpha granules and released on activation, functioning primarily as a recruitment signal that drives fibroblast migration, proliferation, and angiogenesis
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Platelet-rich fibrin
BioChemEntityPlatelet‑rich fibrin is an autologous fibrin matrix that traps platelets, leukocytes, and growth factors, releasing them slowly over 7–14 days for longer activity than PRP.
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Platelet-Rich Plasma
BioChemEntityA concentrated blood-derived preparation containing 3-5 times normal platelet levels, rich in growth factors that signal tissue repair and collagen synthesis.
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Skin microbiome
BioChemEntityThe community of microbes on the skin that shapes barrier function by regulating pH, aiding ceramide production, tuning innate immunity, and preventing pathogen overgrowth.
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Staphylococcus aureus
BioChemEntityA gram-positive, facultatively commensal bacterium that becomes the dominant skin pathogen in dysbiotic conditions.
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Staphylococcus epidermidis
BioChemEntityThe dominant commensal bacterium on human skin, once regarded primarily as an opportunistic pathogen but now understood as an active contributor to barrier integrity and antimicrobial defence.
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Vascular endothelial growth factor
BioChemEntityThe primary angiogenic growth factor in skin, produced by keratinocytes, dermal fibroblasts, and dermal papilla cells and stored in platelet alpha granules.
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Vitreoscilla filiformis
BioChemEntityA TLR2‑activating bacterial lysate that boosts epidermal AMP and antioxidant genes and improves barrier function and S. aureus colonisation in atopic dermatitis.