Senescence-associated secretory phenotype
MedicalConditionThe pro‑inflammatory secretory programme of senescent cells, releasing cytokines and MMPs that degrade collagen, suppress regeneration, and drive chronic tissue inflammation.
Medical Condition
4 entities in this category
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4 entities found in MedicalCondition starting with S Clear filters
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Skin barrier dysfunction
MedicalConditionBarrier dysfunction describes the full spectrum of stratum corneum failure, from the earliest detectable impairment of moisture retention to the self-perpetuating inflammatory cycle.
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Skin dysbiosis
MedicalConditionA state of microbial community imbalance on the skin surface, characterised by loss of commensal species, reduced diversity, and conditions that permit pathogenic overgrowth.
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Solar elastosis
MedicalConditionThe accumulation of disorganised, non-functional elastotic material in the upper dermis, representing the defining histological marker of photoaged skin.