Thymic stromal lymphopoietin
ProteinA keratinocyte‑derived alarmin that translates barrier disruption into Th2 immune activation, driving itch, mast‑cell priming, and the atopic inflammatory cascade.
Protein
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Transforming growth factor beta
ProteinTGF-β is a pleiotropic cytokine and the master regulator of wound healing, fibrosis, and extracellular matrix remodelling in skin.
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Tumour necrosis factor
ProteinTNF is a pro-inflammatory cytokine produced by macrophages, adipocytes, and T-cells that acts through NF-κB to amplify and sustain inflammatory signalling.