Insulin
ProteinA β‑cell–derived anabolic hormone that regulates glucose uptake, lipid storage, and tissue growth, with chronic hyperinsulinaemia producing metabolic effects before overt hyperglycaemia.
6 entities in this category
6 entities found in Protein starting with I Clear filters
A β‑cell–derived anabolic hormone that regulates glucose uptake, lipid storage, and tissue growth, with chronic hyperinsulinaemia producing metabolic effects before overt hyperglycaemia.
A growth factor produced primarily by dermal fibroblasts and dermal papilla cells, with roles spanning fibroblast proliferation, keratinocyte migration, collagen stabilisation, and angiogenesis.
Inflammatory cytokine that suppresses production of barrier proteins including filaggrin and claudin-1.
IL‑33 is an epithelial‑derived “alarmin” cytokine released from stressed or damaged barrier tissues, including keratinocytes in the skin.
Inflammatory cytokine that suppresses barrier protein production, perpetuating barrier dysfunction during inflammatory skin conditions.
A pleiotropic cytokine with context-dependent pro- and anti-inflammatory effects determined by which receptor complex mediates signalling.