Gamma-linolenic acid
MolecularEntityAn omega-6 fatty acid produced from linoleic acid via delta-6 desaturase, and the precursor to DGLA. GLA generates predominantly anti-inflammatory mediators.
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17 entities found starting with G Clear filters
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Ghrelin
ProteinThe 'hunger hormone' produced by the stomach, stimulating appetite particularly for energy-dense foods during caloric restriction.
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Ghrelin rebound
BiologicalProcessPhenomenon where hunger hormone levels spike after stopping GLP-1 medications, sometimes exceeding pre-treatment levels.
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GLP-1 medication discontinuation
BiologicalProcessStopping GLP-1 medication (tirzepatide or semaglutide), which typically leads to appetite signal changes and potential weight regain.
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Glucagon-like peptide-1
ProteinNatural satiety hormone produced in the gut, signalling fullness to the brain and forming the basis for GLP-1 medication effects.
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Gluconolactone
ChemicalSubstanceA gentle PHA that chelates minerals, lightly exfoliates, hydrates, and provides antioxidant activity, with surface‑limited penetration ideal for sensitive skin.
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Glucose-dependent insulinotropic polypeptide
ProteinThe first and dominant incretin hormone, responsible for 60 to 80% of the postprandial insulin response, that, unlike GLP-1, acts directly on adipose tissue to promote lipid storage.
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Glucosylceramidase
ProteinThe extracellular processing enzyme that converts glucosylceramide to free ceramide in the lower stratum corneum. One of two enzymes completing the final step of ceramide generation.
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Glycation
BiologicalProcessNon‑enzymatic binding of sugars to proteins, forming AGEs that accumulate, cross‑link structural proteins, and drive inflammatory and oxidative damage via RAGE.
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Glycation-related skin changes
BiologicalProcessSkin dullness, yellowing, stiffness, and slowed repair caused by long‑term AGE buildup, producing a pattern distinct from chronological ageing or UV damage.
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Glycerin
ChemicalSubstanceHighly effective humectant that draws moisture into skin from the environment and deeper tissue layers.
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Glycine
ChemicalSubstanceThe smallest amino acid and the most abundant in collagen, occupying every third position in the triple-helix structure.
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Glycolic acid
ChemicalSubstanceAlpha-hydroxy acid (AHA) that dissolves bonds between dead skin cells, accelerating cell turnover and improving skin texture.
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Glycosaminoglycan
BioChemEntityGlycosaminoglycans (GAGs) are the dermis's primary humectants, binding water, while also organising collagen architecture and regulating growth-factor and cytokine signalling.
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Growth arrest-specific protein 6
ProteinGrowth factor involved in hair follicle signalling and cellular processes relevant to hair cycle regulation.
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Gut microbiota
BiologicalProcessThe community of gut microorganisms that modulates immune signalling, inflammation, and microbial metabolites with downstream effects on skin barrier function and disease risk.
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Gut-skin axis
BiologicalProcessThe bidirectional communication system linking gut microbiota, immune signalling, and microbial metabolites to skin inflammation, barrier function, and disease susceptibility.